The effect of concussion on cerebral uptake of 2-deoxy-d-glucose in rat
Identifieur interne : 005041 ( Main/Exploration ); précédent : 005040; suivant : 005042The effect of concussion on cerebral uptake of 2-deoxy-d-glucose in rat
Auteurs : Kanhaiya R. Shah [Canada] ; Michael West [Canada]Source :
- Neuroscience Letters [ 0304-3940 ] ; 1983.
Abstract
The effect of concussion on 2-deoxy-d-glucose uptake by various regions of rat brain was investigated. The relative uptake of 2-deoxy-d-glucose was measured at 10 and 20 min post-concussion. The uptake did not change significantly from control rats at 20 min post-concussion. This may be reflective of transient nature of concussion. The uptake was higher in cortex and lower in subcortical structures at 10 min post-concussion. These changes are similar to those reported in spreading cortical depression. Spreading cortical depression may thus be a component of concussion mechanism.
Url:
DOI: 10.1016/0304-3940(83)90053-8
Affiliations:
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<front><div type="abstract" xml:lang="en">The effect of concussion on 2-deoxy-d-glucose uptake by various regions of rat brain was investigated. The relative uptake of 2-deoxy-d-glucose was measured at 10 and 20 min post-concussion. The uptake did not change significantly from control rats at 20 min post-concussion. This may be reflective of transient nature of concussion. The uptake was higher in cortex and lower in subcortical structures at 10 min post-concussion. These changes are similar to those reported in spreading cortical depression. Spreading cortical depression may thus be a component of concussion mechanism.</div>
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